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Framework Desktop Ryzen AI Max+ 395 128GB vs Mac Studio M4 Max 64GB

For running models locally, priced in the US. At 32k context the first runs 41 models fully in memory, the second 34.

In short

The Framework Desktop Ryzen AI Max+ 395 128GB has more memory for models: 128 GB against 64 GB. At 32k context the Framework Desktop Ryzen AI Max+ 395 128GB runs 41 of the models we track fully in memory and the Mac Studio M4 Max 64GB 34; only the Framework Desktop Ryzen AI Max+ 395 128GB holds DeepSeek V4 Flash. On the models both run fully in memory, the Mac Studio M4 Max 64GB is about 2.5× as fast as the Framework Desktop Ryzen AI Max+ 395 128GB (estimated, median across models). In the US the Framework Desktop Ryzen AI Max+ 395 128GB costs $3,449 at eBay (used) and the Mac Studio M4 Max 64GB $3,400 at eBay: the Mac Studio M4 Max 64GB is $49 cheaper.

Updated . Speeds are estimates; how they are worked out.

Framework Desktop Ryzen AI Max+ 395 128GB

$3,449

eBay, used (asking)

Add to build
Mac Studio M4 Max 64GB

$3,400

eBay

Add to build

Specifications

SpecFramework Desktop Ryzen AI Max+ 395 128GBMac Studio M4 Max 64GB
ChipRyzen AI Max+ 395 (Radeon 8060S)Apple M4 Max (40-core GPU)
Memory bus256-bit512-bit
Memory bandwidth256 GB/s546 GB/s
FP16 compute59.4 TFLOPS16.16 TFLOPS
SoftwareROCmMetal
Unified memory128 GB64 GB
GPU can use by default96 GB48 GB
GPU can use, tuned120 GB56 GB
Operating systemlinuxmacos
ProcessorRyzen AI Max+ 395M4 Max 16-core
Storage1000 GB1000 GB

What each runs

Estimated decode speed with the most precise quant that fits each one est.

ModelFramework Desktop Ryzen AI Max+ 395 128GBMac Studio M4 Max 64GB
DeepSeek V4 Flash9tok/sUD-Q2_K_XLwon't run
Qwen 3.8 Flash Next3tok/sUD-Q3_K_XLwon't run
MiniMax M2.77tok/sUD-Q2_K_XLwon't run
Qwen 3.8 27B5tok/sQ8_011tok/sQ8_0
Qwen 3.5 122B-A10B9tok/sQ6_K50tok/sUD-Q2_K_XL
Qwen 3.6 27B5tok/sQ8_012tok/sQ8_0
gpt-oss 120B20tok/sMXFP4won't run
Qwen3 Coder Next17tok/sQ8_066tok/sQ4_K_M
Nemotron 3 Super 120B-A12B10tok/sUD-Q4_K_Mwon't run
Gemma 4 31B4tok/sQ8_010tok/sQ8_0
Mistral Small 4 119B13tok/sUD-Q6_K68tok/sUD-Q2_K_XL
Qwen 3.6 35B-A3B22tok/sQ8_056tok/sQ8_0
Qwen 3.5 27B5tok/sQ8_012tok/sQ8_0
Gemma 4 26B-A4B17tok/sQ8_042tok/sQ8_0
GLM 4.5 Air4tok/sQ5_K_Mwon't run
Qwen 3.5 35B-A3B22tok/sQ8_056tok/sQ8_0
Qwen3 Next 80B-A3B21tok/sQ8_080tok/sQ4_K_M
GLM 4.7 Flash12tok/sQ8_030tok/sQ8_0
Devstral Small 2 24B5tok/sQ8_012tok/sQ8_0
Nemotron 3.5 Lightning 30B-A3B24tok/sUD-Q6_K_XL60tok/sUD-Q6_K_XL
gpt-oss 20B26tok/sMXFP466tok/sMXFP4
Kimi Linear 48B-A3B24tok/sQ8_077tok/sQ6_K
Qwen3 Coder 30B-A3B13tok/sQ8_033tok/sQ8_0
Qwen3 32B3tok/sQ8_08tok/sQ8_0
Gemma 4 12B10tok/sQ8_026tok/sQ8_0
Qwen 3.5 9B13tok/sQ8_033tok/sQ8_0
Mistral Small 3.2 24B5tok/sQ8_012tok/sQ8_0
Gemma 3 27B4tok/sQ8_011tok/sQ8_0
DeepSeek R1 Distill Qwen 32B3tok/sQ8_08tok/sQ8_0
Llama 3.3 70B2tok/sQ8_0won't run
Ministral 3 14B7tok/sQ8_018tok/sQ8_0
Qwen3 14B7tok/sQ8_017tok/sQ8_0
DeepSeek R1 0528 Qwen3 8B10tok/sQ8_026tok/sQ8_0
Qwen3 8B10tok/sQ8_026tok/sQ8_0
Phi-4 14B6tok/sQ8_016tok/sQ8_0
Qwen 3.5 4B25tok/sQ8_063tok/sQ8_0
Ministral 3 8B10tok/sQ8_026tok/sQ8_0
Granite 4.2 8B10tok/sQ8_024tok/sQ8_0
Gemma 4 E4B15tok/sQ8_039tok/sQ8_0
LFM2.5 8B-A1B32tok/sQ8_080tok/sQ8_0
Llama 3.1 8B13tok/sQ6_K33tok/sQ6_K
GLM 5.3 Flashwon't runwon't run

Questions

Which is better for local AI, the Framework Desktop Ryzen AI Max+ 395 128GB or the Mac Studio M4 Max 64GB?
Choose the Framework Desktop Ryzen AI Max+ 395 128GB to run bigger models. Choose the Mac Studio M4 Max 64GB for speed. Choose the Mac Studio M4 Max 64GB to spend less.
Which can run bigger models, the Framework Desktop Ryzen AI Max+ 395 128GB or the Mac Studio M4 Max 64GB?
At 32k context the Framework Desktop Ryzen AI Max+ 395 128GB runs 41 of the models we track fully in memory and the Mac Studio M4 Max 64GB 34; only the Framework Desktop Ryzen AI Max+ 395 128GB holds DeepSeek V4 Flash.
Which is faster for local AI, the Framework Desktop Ryzen AI Max+ 395 128GB or the Mac Studio M4 Max 64GB?
On the models both run fully in memory, the Mac Studio M4 Max 64GB is about 2.5× as fast as the Framework Desktop Ryzen AI Max+ 395 128GB (estimated, median across models).
What is the price difference between the Framework Desktop Ryzen AI Max+ 395 128GB and the Mac Studio M4 Max 64GB?
In the US the Framework Desktop Ryzen AI Max+ 395 128GB costs $3,449 at eBay (used) and the Mac Studio M4 Max 64GB $3,400 at eBay: the Mac Studio M4 Max 64GB is $49 cheaper.

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